Early Detection of Hepatocellular Carcinoma on top of Liver Cirrhosis: The Fas Receptor and Ligand System
نویسندگان
چکیده
1 Department of Pathology, Theodor Bilharz Research Institute, Cairo, Egypt 2 Department of Hematology , Theodor Bilharz Research Institute, Cairo, Egypt 3 Advanc Dental/Medical institute IPPT,USM, Malysia & Medicinial Chemistry Department of NRC,Cairo, Egypt 4 Department of Surgery. Faculty of Medicine (Kasr El Aini Hospital), Cairo University, Egypt 5 Department of Electron Microscop (Hematology), Theodor Bilharz Research Institute, Cairo, Egypt 6 Department of Hepatology & Gasteroenterology, Theodor Bilharz Research Institute, Cairo, Egypt. Address for correspondence : Theodor Bilharz Research Institute, Cairo, Egypt
منابع مشابه
The Role of Fas/Fas Ligand System in the Pathogenesis of Liver Cirrhosis and Hepatocellular Carcinoma
BACKGROUND The Fas receptor/ligand system including soluble forms is the most important apoptotic initiator in the liver. Dysregulation of this pathway may contribute to abnormal cell proliferation and cell death and is regarded as one of the mechanisms preventing the immune system from rejecting the tumor cells. OBJECTIVES To analyze the role of Fas system Fas/ Fas ligand (Fas/ FasL) in the ...
متن کاملAllantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions
Objective(s): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective. Allantoin is one of the principal compounds in many plants and an imidazoline I receptor agonist as well. Allantoin has positive eff...
متن کاملبررسی اثر توکسیسیته عصاره الکلی زنجبیل تازه بر سلول های سرطانی کبد
Introduction & Objective: Hepatocellular carcinoma (HCC, also called malignant hepatoma) is a primary malignancy (cancer) of the liver. Most cases of HCC are secondary to either a viral hepatitic infection (hepatitis B or C) or cirrhosis (alcoholism being the most common cause of hepatic cirrhosis. Recently, the biological activities of zingiber officieale plants have been reported as possess...
متن کاملEvaluation of serum AFP (α-fetoprotein) level in HBsAg carrier patients for diagnosis of hepatocellular carcinoma
Background: Hepatocellular carcinoma (HCC) is common all over the world as well as Iran. The incidence of HCC is higher in hepatitis B carriers and it is highly recommended to periodically screen these patients by serum alpha-fetoprotein (AFP) and liver ultrasound (US) every 6 months. We explore the diagnostic accuracy and the performance of (AFP) in cases of hepatitis B carriers as a scree...
متن کاملComparison of hepatitis C virus risk factors in genotypes 1a and 3a
Background: One of the most important causes of chronic liver disease is hepatitis C virus (HCV), which causes liver cirrhosis and hepatocellular carcinoma. To control the prevalence of the disease, knowledge and information in risk factor of HCV are required. The aim of this study was to compare the risk factors of infection between HCV patients with genotypes 1a and 3a. Methods: This is an o...
متن کامل